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You’ll receive free e-mail news updates each time a new story is published. Researchers at Yale University are controlling the brains of normal mice and turning them into killing machines. (Monica Akhtar/The Washington Post) You've never seen such a sight in your life. A team of scientists used brain control to turn about a dozen ordinary mice into killing machines. They employed a technique called optogenetics that manipulates neurons using light to make the fluffy critters go all Hulk on prey. With the light switched off, the mice were mostly chill, sometimes even scurrying around their cages to avoid prey or toys made to resemble prey. But when the switch was on, things got ugly. Crickets in cages were attacked and beheaded, and plastic toys that looked like prey received powerful bites that would've been lethal. The scientists are not trying to create a monster. “Basically, we are trying to understand how large brain networks work,” said Ivan de Araujo, an author of the study, published Thursday in the journal Cell. Araujo, an associate professor of psychiatry and physiology at Yale University, and his co-authors, Wenfei Han of Yale and Milton Canteras, a neurobiologist at the University of São Paulo, sought to answer a long-standing question in their field: What parts of the brain trigger certain motor responses. In neurobiology, studying the complex brain functions that govern predatory behavior is a good way to do that.
For the original version including any supplementary images or video, visit https://www.washingtonpost.com/news/speaking-of-science/wp/2017/01/12/scientists-used-light-to-turn-mice-into-stone-cold-killers/
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